#Merlin project 3.1 software#

Once the file has bee formatted, One may plot the PCoA results using ggplot2 library in R software using the below commands:Introduction* The$seriesof$practicalsthisafternoon$and$tomorrow$morning$will$introduce$you$to$ analyzing$Genome$Wide$Association$Study(GWAS)datasetsusing$a$programThe GWAS method is commonly applied within the social sciences. txt file and edit in MS Excel to add the below header and information to plot in ggplot2. Optional step: Plotting in R using ggplot2. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. 1.3 Phenotype distribution plot It is always a wise idea to look at the phenotype distribution by plotting to check for any outliers.Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Tip! Both files can be opened at same time holding CTRL and clicking the file names. The AnnotateLocus.py of PAINTOR is applied to SNPs from the same chromosome, so you either split the GWAS file into chromosomes or split it into loci in order to use AnnotateLocus.py to generate functional annotation matrix Step 1.2: Importing phenotype and genotype files Import the files by following the steps shown below. Usually this step is complex and time consuming, and this tutorial will focus on this step.

Merlin project 3.1